My Music Machines takes top honor for largest jump in NIH funding in the Capital District

Our company was highlighted by the Center for Economic Growth as the leading company for NIH funding growth in 2017 in this article.

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Capital Region Federal Life Sciences Grant Haul Reaches 4-Year High

Wadsworth Center scores most funding since FY2012

As New York State launched a $650 million initiative to grow its life sciences cluster, Capital Region academic institutions, nonprofits and private firms in fiscal 2017 netted their largest haul of National Institutes of Health (NIH) funds in four years. Regionwide, NIH awarded 124 grants totaling $54.6 million, up 1.1 percent from fiscal 2016, according to a Center for Economic Growth (CEG) analysis of NIH’s Research Portfolio Online Reporting Tools(RePORT) database.*

Biggest Gainers

In fiscal 2017, the Capital Region had a dozen NIH awardees with over $1 million in total NIH funding. The New York State Department of Health’s Wadsworth Center, Albany Medical College, the University at Albany and Rensselaer Polytechnic Institute were the region’s NIH grant rainmakers, accounting for $40 million, or 64 percent of total funding. Three quarters (75.7 percent) of all funding went to Capital Region academic institutions, government agencies and nonprofit organizations. Small firms accounted for 14.9 percent of the total and larger firms, such as GE Global Research and Albany Molecular Research Inc. (AMRI), accounted for 9.4 percent.

Driving last year’s growth in NIH funding were AMRI (up $2 million or 104.6 percent), the Wadsworth Center (up $1.3 million or 10.8 percent), the Albany College of Pharmacy and Health Sciences (up $960,000 or 200 percent) and SUNY Polytechnic Institute (up $779,524 or 54.4 percent). With $12.8 million from 25 awards, the Wadsworth Center led the region in both NIH awards and total funding. That marked Wadsworth’s largest NIH haul since fiscal 2012, and it came as the state Department of Health is preparing to consolidate the center’s five laboratories in the region into a single campus.

Startup Successes

My Music Machines, a Scotia-based startup, emerged as the region’s fastest-growing NIH awardee, experiencing a 344.2 percent annual increase in funding. The firm received $999,500 in Small Business Technology Transfer (STTR) Phase II funding to develop a respiratory therapy that “uses interactive gaming and music to encourage patient compliance.” The firm’s Jamboxx technology is designed to help post-operative surgery patients as well as people suffering from quadriplegia and other spinal cord injuries; high-level motor neuron diseases, such as ALS and multiple sclerosis; and disorders such as cystic fibrosis.

HocusLocus, a SUNY Poly spinoff that focuses on post-transcriptional regulation of RNA, secured a $733,710 STTR Phase II grant. That grant was the largest of the five it has received from NIH since 2011. The funding will support efforts to leverage post-transcriptional regulation to replace antiquated bio-manufacturing techniques and improve the production yield of biological products such as antibodies, vaccines and proteins by up to 50 percent.

Simmetrix, a Clifton Park software developer, also received its first NIH grant. Traditionally, Simmetrix has provided simulation-based design engineering solutions to manufacturers and advanced R&D firms. But in fiscal 2017 Simmetrix received $149,448 from NIH for the improvement and automation of the 3D traction force microscopy process. Those developments aim “to quantify cellular tractions that can be used to better understand the role of tractions in biomechanical signaling and in the design new therapeutic interventions that target these pathways.”

Awarding Institutes and Centers

With $9.7 million in awards, the National Institute of General Medical Sciences (NIGMS) was the region’s top awarding NIH awarding institute. That represented a 12.2 percent annual increase. The National Institute of Allergy and Infectious Diseases (NIAID), which had been the region’s top awarding institution in fiscal 2016, trailed NIGMS in fiscal 2017 with $9.6 million in awards. The National Institute of Dental and Craniofocal Research (NIDCR) experienced the largest jump in the amount of funding it awarded in the region – 125.9 percent to $1.1 million. The National Institute of Neurological Disorders and Stroke (NINDS) also saw a 64.4 percent increase in funds awarded to $5.1 million. That made NINDS the region’s fourth largest awarding institute, behind the National Heart, Lung and Blood Institute (NHLBI) at to $6.6 million.

CEG and the Life Sciences

In its 2017 Progress Report, the Capital Region Economic Development Council (CREDC) identified CEG as playing a vital role in supporting the state initiative of growing the area’s life sciences cluster. Under the CREDC’s Life Sciences Cluster Plan, the CREDC said CEG will leverage its 14-year-old life sciences Bioconnex network, its National Institute for Standards and Technology (NIST) Manufacturing Extension Partnership (MEP) center and its status as an Innovate 518 operational partner to do the following:

  • Perform an industry assessment;
  • Develop an R&D asset catalogue;
  • Conduct industry attraction; and
  • Provide support to biotechnology startups.

CEG will also continue to develop this cluster’s talent pipeline through its programming geared toward training workers for careers in advanced manufacturing and Bioconnex’s speed mentoring events for local college students to engage with employees working in the life sciences sector.

Note

* Not included in the regional NIH funding total are grants awarded to out-of-region institutions but that have local principal investigators, such as an Albert Einstein College of Medicine grant that will support research at SUNY Poly for the development of an imaging device for the measurement and control of tumor microenvironments.

Jamboxx